Making Model Microfluidic Devices Using JELL-O
Students create microfluidic devicesCopyright 2011 Michelle Woods, Bioengineering RET Program, School of Engineering, Vanderbilt University
Students create large-scale models of microfluidic devices using a process similar to that of the PDMS and plasma bonding that is used in the creation of lab-on-a-chip devices. They use disposable foam plates, plastic bendable straws and gelatin dessert mix. After the molds have hardened overnight, they use plastic syringes to inject their model devices with colored fluid to test various flow rates. From what they learn, students are able to answer the challenge question presented in lesson 1 of this unit by writing individual explanation statements.
Biomedical, medical, chemical, electrical, mechanical, materials and computer engineers are all involved in assisting biologists and physicians in developing devices that enable us to more easily and efficiently observe and test microscopic cell interactions and reactions. Engineers design microfluidic devices to simulate how the body works and reacts. Microfluidic devices are made by making a master copy, from which an infinite number of copies can be made. Soft lithography is the most common method, and involves the replication of the master in polydimethylsiloxane (PDMS), which is then bonded to a glass microscope slide.
After this activity, students should be able to:
- Describe the method used to make a microfluidic device.
- Develop and create large-scale model "microfluidic" devices.
- Explain the importance and use of microfluidic devices.